NEXTERION® 3-D Polymer coating (P)

The NEXTERION® 3-D Polymer coating is the ideal surface for the covalent immobilization of biomolecules containing primary amines (NH₂ groups) such as proteins, antibodies and most peptides. Furthermore, for amino-modified biomolecules like glycans or oligonucleotides this surface may be the coating of choice.

Product information

SCHOTT specifically developed the 3-D Polymer coating as a dedicated substrate surface for printing low-density antibody microarrays. It produces excellent signal-to-background ratios, and exceptionally wide dynamic ranges compared to conventional "two-dimensional" coatings through a unique combination of low non-specific binding characteristics, and high probe loading capacity. Produced in ISO class 5 clean room conditions using a proprietary thin-film deposition process and running a stringent quality control system, the 3-D Polymer coating is offered in standard and custom formats.

Probe types

• Amino-linked glucans
• Antibodies and antibody fragments
• Functional proteins such as enzymes or receptors
• Small protein fragments such as peptides
• Amino-modified oligonucleotides 16 to 70 mers

Shelf life

Twelve months sealed packages when stored at - 20° C.

Immobilization method

Covalent binding via amine reactive chemistry.