NEXTERION® Aldehydesilane coating (AL)

The NEXTERION® AL coating represents a uniform surface featuring aldehyde groups, that are readily reactive to primary amines in order to bind all types of amino-containing or amino-modified bio-molecules.

Product information

The covalent bond formed at the terminus of the nucleic acid offers both: stability and maximal base pairing opportunity. The covalent binding diminishes sample loss during the course of experiments and permits stringent washing steps, which reduce background noise and allow greater sensitivity. Additional immobilization steps, such as baking or UV cross-linking, are not required for immobilization. Produced in ISO class 5 clean room conditions using a standardized process and running a stringent quality control system, aldehydesilane coated substrates are available in standard and custom formats.

Probe types

• Amino-modified PCR products and BACs/YACs
• Amino-modified oligonucleotides
• Small protein fragments such as peptides

Shelf life

Nine months for sealed packages at room temperature

Immobilization method

Covalent binding via amine reactive chemistry.